3-oxo-5beta-steroid 4-dehydrogenase - meaning and definition. What is 3-oxo-5beta-steroid 4-dehydrogenase
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  3. 3-oxo-5beta-steroid 4-dehydrogenase

What (who) is 3-oxo-5beta-steroid 4-dehydrogenase - definition


3-oxo-5beta-steroid 4-dehydrogenase         
In enzymology, a 3-oxo-5beta-steroid 4-dehydrogenase () is an enzyme that catalyzes the chemical reaction
https://en.wikipedia.org/wiki/3-oxo-5beta-steroid_4-dehydrogenase
5α-Reductase         
  • A side view of 5AR with monoolein and NADPH in the hydrophobic pocket; a view of the 7 transmembrane domains from the top
  • doi = 10.1016/S0960-894X(98)00463-6 }}</ref>
  • doi = 10.2217/fon.10.149 }}</ref> which is why the mechanism shows the NADP+ getting attacked by the enolate formed rather than instant tautamerization occurring like in the case of 5α-reductase's work on testosterone. Finasteride does eventually get released from 5α-reductase enzyme-substrate complex which is why it is not considered a suicide inhibitor as the product eventually formed is dihydrofinasteride.
  • [[Steroidogenesis]], showing both actions of 5α-reductase at bottom center.
ENZYME FAMILY
5 alpha reductase; 5-alpha-reductase; 3-oxo-5a-steroid 4-dehydrogenase; 5 alpha-reductase; 5α-reductase; 3-oxo-5alpha-steroid 4-dehydrogenase; 5a-reductase; 5aReductase; Testosterone 5-alpha-Reductase; 5A-Reductase; 5α-reductase type 2; 5 a Reductase; 5-Alpha reductase; 5AR; EC 1.3.99.5; 3-oxo-5alpha-steroid:acceptor Delta4-oxidoreductase; 5-alpha reductase
5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in three metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism.
https://en.wikipedia.org/wiki/5α-Reductase
3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase         
CLASS OF ENZYMES
3a-hydroxy-5b-androstane-17-one 3a-dehydrogenase; EC 1.1.1.152; 3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase
In enzymology, a 3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase () is an enzyme that catalyzes the chemical reaction
https://en.wikipedia.org/wiki/3alpha-hydroxy-5beta-androstane-17-one_3alpha-dehydrogenase
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